The signs and symptoms of SM
There may be a variety of unexplained, recurring symptoms of systemic mastocytosis (SM) that can span across multiple organ systems.
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There may be a variety of unexplained, recurring symptoms of systemic mastocytosis (SM) that can span across multiple organ systems.
SM is associated with a range of symptoms throughout the body. Symptoms vary in nature since they can be severe, unpredictable, unexplained, and recurring. It's important to remember that different people may experience different symptoms.
The following are some of the common symptoms of SM:
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*This is not an exhaustive list of symptom categories.
Neuropsychiatric
Brain fog, anxiety, depression, difficulty concentrating, memory loss, headaches, or difficulty sleeping.
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Gastrointestinal
Abdominal pain or cramping, recurring diarrhea, heartburn or acid reflux, nausea, vomiting.
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Cardiovascular
Low blood pressure (hypotension), heart “flutters” (palpitations), rapid heart rate (tachycardia), chest pain, dizziness or light-headedness, fainting from anaphylaxis.
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Respiratory
Nasal congestion, shortness of breath, wheezing, throat itching, or swelling.
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Musculoskeletal
Bone pain, muscle pain, bone loss, weak and brittle bones that may break or fracture easily.
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Dermatological
Rashes that appear like red or brown “spots” (urticaria pigmentosa or cutaneous mastocytosis), rashes that may become swollen or itchy, skin that swells up if it becomes scratched, redness in the face or chest that lasts more than a few minutes, or hives.
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Systemic
Extreme unexplained fatigue, weakness, weight loss, sweats, chills, general feeling of ickiness (malaise), severe whole-body allergic reactions (anaphylaxis).
Close ✕*This is not an exhaustive list of symptom categories.
Symptoms in different parts of the body can look a lot like other issues:
Frequent diarrhea and stomach aches can look like any gastrointestinal disorder.
Symptoms, which may appear like an allergic reaction, that seem to be triggered by anything or other reactions that suddenly go from zero to overdrive.
Long-lasting flushing and heartburn can sometimes feel like a sensitivity to certain foods.
Could systemic mastocytosis be hiding in your symptoms? Take the quiz to learn more about the signs and symptoms of SM.
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Learning more can help you along your journey. Here are more topics that may help.
This website does not provide medical advice and is for educational purposes only.
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