Symptoms Triggers Medications Result
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Great job!

You have completed the SM Symptom Quiz.

Remember, only a doctor can provide a diagnosis of SM. The outcome of this quiz is neither a diagnosis nor medical advice. It is intended to be an educational tool to provide understanding of symptoms, triggers, and medications associated with SM.

·

SM is a rare condition affecting approximately 32,000 people in the U.S. (or 0.01% of the population).1 The symptoms, triggers, and medications listed in this quiz may be associated with a variety of other conditions.

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Discussing your symptoms with your doctor can help them determine whether or not they may be related to SM.

Reference: 1: Data on file. Blueprint Medicines Corporation, Cambridge, MA 2022.
Have you experiencedany of the following?
Check all the boxes that apply to you.
Airway symptoms
Nasal congestion, shortness of breath, wheezing, throat itching, or swelling.
Anaphylaxis
An extreme allergic reaction that may have resulted in fainting or dizziness, the use of epinephrine autoinjector, or a visit to the emergency room.
Bone or muscle symptoms
Bone pain, muscle pain, bone loss, or weak and brittle bones that break easily.
Gut symptoms
Abdominal pain, cramping, diarrhea, nausea, vomiting, bloating, heartburn, or acid reflux.
Head or brain symptoms
Brain fog, difficulty concentrating, anxiety, depression, difficulty sleeping, or headaches.
Heart symptoms
Low blood pressure, rapid heart rate, chest pain, dizziness, or fainting.
Skin symptoms
Red or brown, spot-like rashes that become swollen or itchy, skin that swells up if it gets scratched, flushing that lasts more than a few minutes, or hives.
Whole-body symptoms
Extreme fatigue, weakness, weight loss, sweats, chills, or enlarged organs.
None of these
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Alcohol
Bee sting
Certain food or drinks
Certain smells or perfumes
Exercise
Infections
Insect bite
Stress (emotional, physical, environmental)
Other
None of these
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Allergy Medicines
For example: Claritin® (loratadine), Allegra® (fexofenadine), Benadryl® (diephenhydramine), or Zyrtec® (cetirizine)**
Yes
No
Antacids
For example: Pepcid® (famotidine)**
Yes
No
Corticosteroids
For example: prednisone
Yes
No
Mast Cell Stabilizers
For example: Gastrocrom® (cromoglicic acid), NasalCrom® (cromoglicic acid), or Zaditor® (ketotifen)**
Yes
No
Leukotriene Inhibitors
For example: Accolate® (zafirlukast), Singulair® (montelukast), Zyflo® (zileuton)**
Yes
No
Proton Pump Inhibitors
For example: Prilosec® (omeprazole), Prevacid® (lansoprazole), Nexium® (esomeprazole)**
Yes
No
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SUMMARY OF YOUR ANSWERS
Symptoms

A key feature of systemic mastocytosis (SM) is having multiple symptoms in different parts of the body.

You answered:
Triggers

For people with SM, symptom triggers can seem unpredictable and may even change over time.

You answered:
Medications

For people with SM, many symptom-directed medications require frequent dosing and a high daily pill burden.

You answered:
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*This quiz is not medical advice and is not intended for use in the diagnosis of any disease. Your answers may help you identify some of the symptoms you are experiencing and facilitate a discussion with your doctor to help them determine if your symptoms may be associated with SM. The symptoms in this quiz may also be associated with a variety of other conditions, both rare and more common. Remember to talk to your doctor about any symptoms or other concerns you may have about your health.